What is SELPHYL®?

The SELPHYL® System is a kit that allows your doctor to rapidly and safely prepare PRFM in a medical office.

How is PRFM different from PRP?

PRP, by definition is platelets and plasma, where the platelet concentration is generally considered to be twice the normal. PRP should have little to no red blood cells and white blood cells. By adding the precise amount of calcium chloride, the SELPHYL® System can convert the liquid PRP into PRFM, a gel-like matrix. This occurs because the calcium chloride initiates the conversion of fibrinogen to fibrin, as part of the clotting cascade. The fibrin matrix serves as a three dimensional scaffold to maintain the platelets at the site of injection.

The main advantages and benefits of PFRM include:

Where is SELPHYL® available?

SELPHYL® is only available through qualified healthcare practitioners. Over 350 physicians and clinics worldwide currently feature the SELPHYL® System.

Has the SELPHYL® System been reviewed by a regulatory authority?

The Cascade Medical FIBRINET System was cleared for marketing under premarket notification (510(k)) submission numbers BK020051 and BK060006. Cascade Medical Enterprises, LLC has entered into a licensing agreement with Aesthetic Factors, LLC whereby Aesthetic Factors, LLC markets the FIBRINET® Autologous Fibrin & Platelet System in the U.S. under the trade name SELPHYL®. The CE mark certification has been granted in Europe.